intercellular adhesion molecules การใช้

• The protein encoded by this gene is a member of the intercellular adhesion molecule ( ICAM ) family.
• The protein encoded by this gene is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells.
• Intercellular adhesion molecule 1 ( ICAM-1 ) has a central role in airway inflammation in asthma, and it is the receptor for 90 % of Human rhinoviruses.
• Dr . Springer is best known for his pioneering work in discovering the first integrins and intercellular adhesion molecules ( ICAMs ) and elucidating how these cell adhesion molecules function in the immune system.
• The heart attack victims were 80 percent more likely than other carefully matched study participants to have high levels of a substance called ICAM-1, an acronym for intercellular adhesion molecule, type 1.
• LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 ( intercellular adhesion molecules 1 through 3 ), and also functions in lymphocyte costimulatory signaling.
• Pharmacological inhibition of ET B R increased T cell adhesion to endothelial cells in an intercellular adhesion molecule-1 ( ICAM-1 )  dependent manner, increasing TIL numbers in mice and a corresponding tumor response.
• PfEMP1 can bind other endothelial receptors-thrombospondin ( TSP ) and intercellular adhesion molecule 1 ( ICAM-1 )  in addition to CD36-and genes other than PfEMP1 also bind to CD36 : cytoadherence linked protein ( clag ) and sequestrin.
• Luck played an important part in the story of a molecule known by the name of intercellular adhesion molecule 1, or ICAM-1 _ one of a group of molecules that sit on the surface of cells and adhere to other cells when the need arises.
• The binding of XNAs ultimately leads to the development of a procoagulant state, the secretion of inflammatory cytokines and chemokines, as well as expression of leukocyte adhesion molecules such as E-selectin, intercellular adhesion molecule-1 ( ICAM-1 ), and vascular cell adhesion molecule-1 ( VCAM-1 ).
• The late phase of a Type 1 reaction ( which develops 8 12 hours and is mediated by mast cells ) The products of the early phase reaction include chemokines and molecules that act on endothelial cells and cause them to express Intercellular adhesion molecule ( such as vascular cell adhesion molecule and selectins ), which together result in the recruitment and activation of leukocytes from the blood into the site of the allergic reaction.
• Liu H, Carrington M, Wang C, Holte S, Lee J, Greene B, Hladik F, Koelle DM, Wald A, Kurosawa K, Rinaldo CR, Celum C, Detels R, Corey L, McElrath MJ, Zhu T ( 2006 ) Repeat-region polymorphisms in the gene for the dendritic cell-specified intercellular adhesion molecule-3-grabbing nonintegrin-related molecule : effects on HIV-1 susceptibility ., Journal of Infectious Diseases, 193, 698-702
• For the treatment of rheumatoid arthritis, inhibition of DHFR is not thought to be the main mechanism, but rather multiple mechanisms appear to be involved, including the inhibition of enzymes involved in purine metabolism, leading to accumulation of adenosine; inhibition of T cell activation and suppression of intercellular adhesion molecule expression by T cells; selective down-regulation of B cells; increasing CD95 sensitivity of activated T cells; and inhibition of methyltransferase activity, leading to deactivation of enzyme activity relevant to immune system function.